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A Pfizer office in Puurs, Belgium, on Dec. 2, 2022.JOHANNA GERON/Reuters

Pfizer PFE-N on Tuesday said it will launch a cost-cutting program if its COVID-19 vaccine and antiviral treatment keep underperforming expectations in the coming months due to plunging demand.

Pfizer said it anticipates more clarity on the future size of the COVID market later this year as infection rates rise in the autumn and the U.S. switches to a commercial market from government contracts for the vaccine.

Chief Executive Albert Bourla said this fall’s COVID-19 vaccination rates should be a good predictor of what annual rates will look like going forward, “with the only upside if we have a combined vaccine with flu or with RSV, that would increase the vaccination rates.”

If COVID vaccinations are very low this year, the company will scale back its investments for the virus, including combination shots, as part of its cost plan, Bourla said.

Pfizer shares were off about 0.7 per cent in midday trading. Shares of rival vaccine makers Moderna Inc and Novavax, which both rely far more on their COVID-19 shots to drive revenue, were down 2.9 per cent and 5.2 per cent, respectively.

Sales of the COVID-19 vaccine, Comirnaty, which Pfizer shares with German partner BioNTech, fell 83 per cent to $1.49-billion in the second quarter, but came in above analysts’ estimates of $1.40-billion.

Sales of antiviral treatment, Paxlovid, tumbled 98 per cent to $143-million, compared with estimates of $1.08-billion amid low infection rates globally.

The company said its potential cost cuts would be company wide, but mostly focused on its COVID business.

Pfizer trimmed the upper end of its 2023 revenue forecast by $1-billion to $70-billion.

The New York-based drugmaker is also dealing with tornado damage to a warehouse at its Rocky Mount facility, a narrower-than-expected recommendation for its RSV vaccine from regulators, and concern recently approved cancer drug Talzenna may reach a smaller-than-anticipated patient population.

Pfizer, preparing for many top-selling drugs losing patent protection, has responded with acquisitions such as the $43-billion deal for cancer-therapy specialist Seagen to rebuild its product portfolio.

Total revenue for the second quarter fell 54 per cent to $12.73-billion, missing analysts’ estimates of $13.27-billion, according to Refinitiv data.

Excluding items, Pfizer reported a profit of 67 cents per share, topping Wall Street expectations by 10 cents.

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