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Hardcover Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last week | Weeks on List |
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| 1 | The Diamond Eye | Kate Quinn | William Morrow | $24.99 | 1 | 4 |
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| 2 | It Ends with Us | Colleen Hoover | Atria Books | $22.99 | 2 | 22 |
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| 3 | The Paris Apartment | Lucy Foley | William Morrow | $24.99 | 4 | 8 |
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| 4 | Five Little Indians | Michelle Good | HarperCollins Canada | $22.99 | 3 | 4 |
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| 5 | Lessons in Chemistry | Bonnie Garmus | Doubleday Canada | $24.95 | 6 | 2 |
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| 6 | The Long Weekend | Gilly Macmillan | William Morrow | $24.99 | 10 | 3 |
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| 7 | Looking for Jane | Heather Marshall | Simon & Schuster | $24.99 | 7 | 7 |
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| 8 | Bluebird | Genevieve Graham | Simon & Schuster | $24.99 | 5 | 2 |
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| 9 | Sea of Tranquility | Emily St. John Mandel | HarperCollins Canada | $29.99 | 9 | 3 |
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| 10 | One Italian Summer | Rebecca Serle | Atria Books | $24.99 | - | 1 |
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Hardcover Non-Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | Freezing Order | Bill Browder | Simon & Schuster | $36.99 | 9 |
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| 2 | 22 Murders | Paul Palango | Random House Canada | $26.95 | - |
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| 3 | Atlas of the Heart | Brené Brown | Random House | $40.00 | 1 |
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| 4 | My Mother's War | Eva Taylor | Hanover Square Press | $21.99 | 2 |
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| 5 | This Is Assisted Dying | Stefanie Green | Scribner | $24.99 | 4 |
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| 6 | Braiding Sweetgrass | Robin Wall Kimmerer | Milkweed Editions | $26.95 | 6 |
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| 7 | Bittersweet | Susan Cain | Crown | $37.00 | 3 |
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| 8 | Run Towards the Danger | Sarah Polley | Hamish Hamilton | $35.00 | 7 |
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| 9 | Love That Story | Jonathan Van Ness | HarperOne | $34.99 | - |
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| 10 | The Betrayal of Anne Frank | Rosemary Sullivan | HarperCollins Canada | $34.99 | 5 |
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Paperback Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | The Seven Husbands of Evelyn Hugo | Taylor Jenkins Reid | Washington Square Press | $23.00 | 4 |
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| 2 | Spy X Family, Vol. 1 | Tatsuya Endo | Viz Media | $12.99 | - |
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| 3 | Verity | Colleen Hoover | Grand Central Publishing | $22.99 | 5 |
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| 4 | 1st Case | James Patterson; Chris Tebbetts | Grand Central Publishing | $12.99 | 2 |
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| 5 | The Dark Hours | Michael Connelly | Little Brown | $22.99 | 3 |
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| 6 | Nine Lives | Danielle Steel | Delacorte Press | $11.99 | 1 |
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| 7 | Ugly Love | Colleen Hoover | Atria Books | $22.99 | 6 |
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| 8 | Where the Crawdads Sing | Delia Owens | G.P. Putnam's Sons | $24.00 | 7 |
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| 9 | Spy X Family, Vol. 2 | Tatsuya Endo | Viz Media | $12.99 | - |
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| 10 | Sooley | John Grisham | Anchor | $12.99 | - |
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Canadian Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | Five Little Indians | Michelle Good | HarperCollins Canada | $22.99 | 1 |
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| 2 | Looking for Jane | Heather Marshall | Simon & Schuster | $24.99 | 3 |
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| 3 | Bluebird | Genevieve Graham | Simon & Schuster | $24.99 | 2 |
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| 4 | Sea of Tranquility | Emily St. John Mandel | HarperCollins Canada | $29.99 | 4 |
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| 5 | Scarborough | Catherine Hernandez | Arsenal Pulp Press | $19.95 | 5 |
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| 6 | The Maid | Nita Prose | Viking | $24.95 | 6 |
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| 7 | Daughters of the Deer | Danielle Daniel | Random House Canada | $24.00 | 8 |
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| 8 | Sari, Not Sari | Sonya Singh | Simon & Schuster | $22.00 | 7 |
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| 9 | The Circus Train | Amita Parikh | HarperCollins Canada | $24.99 | 10 |
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| 10 | Framed in Fire | Iona Whishaw | TouchWood Editions | $16.95 | - |
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Canadian Non-Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | 22 Murders | Paul Palango | Random House Canada | $26.95 | - |
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| 2 | This Is Assisted Dying | Stefanie Green | Scribner | $24.99 | 2 |
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| 3 | If I Knew Then | Jann Arden | Random House Canada | $19.95 | 1 |
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| 4 | Run Towards the Danger | Sarah Polley | Hamish Hamilton | $35.00 | 4 |
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| 5 | The Betrayal of Anne Frank | Rosemary Sullivan | HarperCollins Canada | $34.99 | 3 |
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| 6 | Finding the Mother Tree | Suzanne Simard | Allen Lane | $34.95 | 7 |
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| 7 | Cat and Nat's Mom Secrets | Catherine Belknap; Natalie Telfer | Penguin Canada | $24.95 | 5 |
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| 8 | 12 Rules for Life | Jordan B. Peterson | Random House Canada | $34.95 | 9 |
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| 9 | Life in the City of Dirty Water | Clayton Thomas-Muller | Allen Lane | $29.95 | 6 |
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| 10 | 21 Things You May Not Know about the Indian Act | Bob Joseph | Indigenous Relations | $19.95 | - |
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Juvenile: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | Cat Kid Comic Club On Purpose | Dav Pilkey | Graphix | $15.99 | - |
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| 2 | Burt the Beetle Doesn't Bite! | Ashley Spires | Kids Can Press | $14.99 | - |
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| 3 | Wings Of Fire: The Flames of Hope | Tui T. Sutherland | Scholastic Press | $22.99 | 1 |
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| 4 | The Good Egg Presents: the Great Eggscape! | Jory John; Pete Oswald | HarperCollins Canada | $13.50 | 2 |
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| 5 | The Bad Guys Movie Novelization | Kate Howard | Scholastic | $8.99 | 10 |
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| 6 | A Good Girl's Guide to Murder | Holly Jackson | Ember | $14.99 | 3 |
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| 7 | Captain Underpants and the Sensational Saga of Sir Stinks-A-Lot: Color Edition (Captain Underpants #12) | Dav Pilkey | Scholastic | $15.99 | 8 |
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| 8 | The Baby-Sitters Club: Good-Bye Stacey, Good-Bye | Ann M. Martin; Gabriela Epstein | Graphix | $16.99 | 5 |
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| 9 | Pop-Up Peekaboo! Things That Go | DK | DK Children | $16.99 | 4 |
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| 10 | Cat Kid Comic Club Perspectives | Dav Pilkey | Graphix | $15.99 | 6 |
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Self-Improvement: April 23, 2022
| Rank | Title | Author | Publisher | List Price | Last Week |
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| 1 | 101 Essays That Will Change the Way You Think | Brianna Wiest | Thought Catalog Books | $18.69 | 2 |
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| 2 | The Mountain Is You | Brianna Wiest | Thought Catalog Books | $22.43 | 5 |
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| 3 | The Subtle Art Of Not Giving A F*ck | Mark Manson | HarperCollins Canada | $23.99 | 4 |
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| 4 | The Gifts of Imperfection | Brené Brown | Hazelden | $22.95 | 3 |
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| 5 | Be a Triangle | Lilly Singh | Doubleday Canada | $24.95 | 1 |
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| 6 | Life Force | Tony Robbins; Peter H. Diamandis; Robert Hariri | Simon & Schuster | $39.99 | 7 |
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| 7 | The 48 Laws of Power | Robert Greene; Joost Elffers | Penguin | $35.00 | - |
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| 8 | Super Gut | William Davis | Collins | $24.99 | 9 |
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| 9 | When You're Ready, This Is How You Heal | Brianna Wiest | Thought Catalog Books | $22.43 | - |
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| 10 | Rich Dad Poor Dad | Robert T. Kiyosaki | Plata | $24.99 | - |
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Historical Fiction: April 23, 2022
| Rank | Title | Author | Publisher | List Price |
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| 1 | Looking for Jane | Heather Marshall | Simon & Schuster | $24.99 |
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| 2 | Bluebird | Genevieve Graham | Simon & Schuster | $24.99 |
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| 3 | Circe | Madeline Miller | Back Bay Books | $22.99 |
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| 4 | Daughters of the Deer | Danielle Daniel | Random House Canada | $24.00 |
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| 5 | The Song of Achilles | Madeline Miller | Ecco | $21.99 |
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| 6 | The Christie Affair | Nina de Gramont | St. Martin's Press | $24.99 |
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| 7 | The Mayfair Bookshop | Eliza Knight | William Morrow Paperbacks | $23.99 |
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| 8 | The Vanished Days | Susanna Kearsley | Simon & Schuster | $24.99 |
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| 9 | The Resistance Girl | Mandy Robotham | Avon Books | $24.99 |
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| 10 | The Last Grand Duchess | Bryn Turnbull | Mira | $21.99 |
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